FDA approved in 2011, Xarelto is one of the latest generations of blood thinning anticoagulants, designed to reduce the risk of blood clots, deep vein thrombosis and pulmonary embolism in patients suffering from atrial fibrillation and in patients undergoing knee or hip replacement surgery. The most dangerous side effect for individuals taking Xarelto is uncontrollable bleeding. Unlike other anticoagulants, currently there is no known antidote to reverse uncontrollable bleeding caused by Xarelto. Other serious injuries could include intracranial hemorrhage, spinal and epidural hematoma, gastrointestinal hemorrhage, adrenal bleeding, stroke, and blood clots. Dangerous Drugs